- Skincare
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- Wrinkles
- Why You Need Vitamin C and Retinol in Your Anti-Aging Routine
To reduce the appearance of wrinkles, fine lines and other signs of aging, vitamin C and retinol are two key ingredients to keep in your arsenal. Vitamin C is known for its brightening benefits, while retinol boosts cell turnover. Using both ingredients in your anti-aging skincare routine can help you achieve a radiant, youthful complexion. To learn how to safely incorporate them, follow our guide below.
Benefits of Vitamin C
L-ascorbic acid, or pure vitamin C, is a powerful antioxidant that helps neutralize free radicals. Triggered by various environmental factors such as pollution, smoke and UV rays, free radicals can break down your skin’s collagen and cause visible signs of aging to form — this can include wrinkles, fine lines, dark spots, dry patches and more. In fact, vitamin C is the only antioxidant proven to stimulate collagen and minimize fine lines and wrinkles, according to the Cleveland Clinic. It also helps address hyperpigmentation and dark spots, and can give you a brighter complexion with continued application.
Benefits of Retinol
Retinol is considered the gold standard of anti-aging ingredients. A derivative of vitamin A, retinol is proven to improve the look of fine lines, wrinkles, skin texture, tone and even acne. “By replenishing the skin with vitamin A, lines can be minimized, as it helps build collagen and elastin,” says Dr. Dendy Engelman, a board-certified dermatologist and Skincare.com expert. Because retinol can cause dryness and irritation, most experts recommend starting with a low concentration of the ingredient and minimal frequency of use to help build up your skin’s tolerance to it. Start by using retinol once or twice a week at night, and gradually increase the frequency as needed to every other night, or every night as tolerated.
How to Use Vitamin C and Retinol in Your Routine
First, you’ll need to pick your products. For vitamin C, dermatologists suggest opting for a high-quality serum with stabilized concentrations of the ingredient. The serum should also come in a dark bottle, as vitamin C can become less effective with exposure to light. One of our current favorites is the Vichy LiftActiv Vitamin C Serum, which contains 15% pure vitamin C as well as hyaluronic acid. The ingredients work together to brighten and hydrate the skin.

When it comes to selecting a retinol, you have a few options. Prescription retinoids — like retinoic acid or tretinoin — are stronger, while over-the-counter retinoids — like retinol or retinyl palmitate — are usually more mild. Both, however, are effective, so choose one that suits your needs and that your dermatologist recommends. If you’re looking for a convenient pick that’s gentle enough for first-time retinol users, reach for the Kiehl’s Retinol Skin-Renewing Daily Micro-Dose Serum.

Do You Apply Retinol Before or After Vitamin C?
Most dermatologists recommend applying vitamin C serums before sunscreen in the morning, when its UV ray- and free radical-fighting benefits can be most effective. Retinol, on the other hand, is an ingredient that should be applied at night, as it can cause skin sensitivity to sunlight. That being said, pairing the two together can be beneficial. “Cocktailing these two ingredients together does make sense,” says Dr. Engelman. In fact, vitamin C can help stabilize retinol and allow it to work more effectively against your aging skin concerns.
However, because retinol and vitamin C are both potent, we recommend combining the two only after your skin is used to them and always with sunscreen. If you have sensitive skin or experience irritation after application, stagger use of the ingredients.
Photo: Shutterstock
Read More:
How Vichy’s Vitamin C Serum Helped Brighten One Editor’s Skin in 10 Days
The Best Retinol Products Available on Amazon
A Simple Skincare Routine for Mature Skin Types
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